Senior Director, Portfolio Strategy, Analytics & Enablement, Cardiometabolic Research

Location: US, Indianapolis IN

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

The Portfolio Strategy, Analytics, & Enablement Lead for Cardiometabolic Research (CMR) will play a critical role in shaping & implementing CMR’s long-term vision, and will drive high-impact initiatives that foster growth, innovation, and operational excellence. As a strategic leader with vision, this individual will develop and implement initiatives that align therapeutic areas & cross-functional teams, ensuring seamless execution of organizational priorities while anticipating and responding to industry trends.

Partnering closely with the CMR Lead Team (LT), they will own the portfolio fact base, regularly assess portfolio health, frame and run priority strategic projects, and support initiatives to improve communications, culture, and capabilities across CMR. This individual will also support efforts to communicate CMR portfolio status and progress across the broader organization, including to senior leadership.

Key Responsibilities

Portfolio strategy

Lead portfolio-level strategy projects for CMR from the initial framing of the question through analysis, synthesis, and a recommendation to the Core Leadership Team. This includes assembling the working team, driving discussions, and delivering actionable outputs.

Develop & maintain an integrated view of the CMR portfolio across therapeutic pillars, covering development stage, therapeutic modality, target novelty, risk-reward profile, and resource load. Use this view to evaluate portfolio health & make recommendations on improvements. This assessment will characterize the portfolio’s risk / reward distribution and project its expected shape as new pillars mature.

Partner with therapeutic area leaders to keep program strategies and learning plans current, and surface cross-portfolio issues such as shared scientific risks, resourcing conflicts, and unexplored white space.

Support the long-range planning cycle by translating CMR strategic priorities into plans, metrics, and dashboards that the Core Leadership Team can manage against through the year.

Own the metrics and dashboards that track progress against CMR strategic objectives and establish them as the shared reference point in leadership discussions.

Track the external landscape relevant to cardiometabolic research, including competitive, scientific, and regulatory developments, and bring the implications into portfolio and planning discussions.

Organizational enablement

Support CMR's organizational communications, including monthly CMR updates to senior leadership, and development of content & execution of CMR-wide town halls in conjunction with therapeutic area leads.

Drive program management and change management for CMR-wide capability initiatives. One example is the Strategic Thinking program, which trains scientists to clarify program strategy, identify and prioritize key issues, and design experiments that resolve them.

Manage recurring organizational processes and campaigns, including the President's Award proposal process.

Basic Requirements

• Bachelor's degree in a life science, quantitative, or business field
• 6+ years of experience in pharmaceutical or biotechnology R&D with roles involving portfolio strategy, portfolio management, decision analytics, or strategy consulting serving those functions.
• Experience leading cross-functional strategy projects from framing through to a leadership decision.

Additional Skills and Preferences

An advanced degree (PhD, PharmD, MS, or MBA)

Working knowledge of drug discovery and early development in cardiometabolic disease (diabetes, obesity, cardiovascular disease, and their complications)

Hands-on experience with portfolio analytics, including risk-adjusted valuation, probability of technical success, and resource and scenario modeling. The strongest candidates will be comfortable partnering with scientists on the quantitative work while owning the strategic framing themselves.

A track record of designing metrics and dashboards that senior leaders rely on

The ability to draw out diverse opinions in a matrixed organization and synthesize them into a recommendation that leadership will act on

Clear written and spoken communication to scientific and non-scientific audiences, including governance committees

A self-motivated individual who combines scientific curiosity with an enterprise mentality and a strong grasp of business concepts

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$160,500 - $235,400

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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Additional Locations: US, Remote