Senior Manager, Evidence & Insights (RWE & HEOR)

At Real Chemistry, making the world a healthier place isn’t just an aspiration—it’s our everyday reality. Our drive to transform healthcare is informed by our blend of deep scientific expertise, human-centred creativity, and AI-driven insights, fostering a unique environment where innovation thrives and our people are impact-obsessed. As a global agency, we provide a full suite of services across healthcare communications and marketing to our clients, including top players in the pharmaceutical and biotech industries.

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Real Chemistry is looking for an Senior Manager join our growing Evidence & Insights team!

The Senior Manager, Evidence & Insights provides strategic and scientific support across real-world evidence (RWE), health economics and outcomes research (HEOR), and evidence generation. This role co-leads client engagements end-to-end, helping to shape evidence strategies, oversee analytics and deliverables, and advise biopharma and related stakeholders.

This is a hybrid role, based in any of our US offices—including New York City, Boston, Chicago, Indianapolis, or San Francisco—or remotely within the US, depending on team and business needs.

What you'll do

Co-lead and support RWE and HEOR strategy across client programs, including evidence planning, study design, and interpretation of findings to inform value, access, and payer and health system decision-making.

Design and support evidence generation plans (e.g., RWE studies, retrospective database studies, economic models) aligned to product lifecycle needs and client requirements.

Develop and oversee the process for systematic literature reviews (SLRs), including the development of study protocols, execution of study searches, delegation of screening, and oversight of data extraction and reporting (leveraging the Nested Knowledge platform where possible).

Translate complex real-world datasets and outcomes evidence into clear, defensible insights and recommendations for clients (clinical, economic, and utilization outcomes).

Serve as a client co-lead alongside Director and VP: build trusted relationships, guide strategic direction, and ensure work products meet scientific rigor, timelines, and client expectations.

Directly manage staff planning, internal and external project timelines, internal and external communications, and budgets to ensure projects are adequately staffed, managed, and executed.

Stay current on evolving evidence standards and trends impacting access decisions, including:

HTA requirements and value frameworks

Payer evidence expectations and comparative effectiveness

• RWE guidance and regulatory considerations
• Measurement/reporting of quality, performance, and outcomes
• Co-lead scoping and resourcing for engagements: define scope of work, timelines, budgets, and staffing plans; proactively manage risks and changes.
• Partner cross-functionally to connect evidence strategy to broader client objectives and account growth.

This position is a perfect fit for you if

• You are adaptable, resilient, and OK with adjusting your scope, responsibilities, and focus as we grow. When things change, so do we. We’re always evolving.
• You are proactive, driven, and resourceful with strong prioritization skills and a desire to dive into the data.
• You are highly organized self-starter, able to work independently and under tight deadlines.

What you should have

3-5+ years of relevant experience in HEOR, RWE, SLR, epidemiology, outcomes research, market access strategy, or closely related fields (consulting and/or biopharma experience preferred).

Bachelor’s degree required; advanced degree strongly preferred (MPH, PhD, PharmD, MD, MS, or equivalent) in health economics, epidemiology, public health, biostatistics, health services research, or related discipline.

Demonstrated expertise in HEOR/RWE study design and execution and ability to translate evidence into access-relevant strategy.

Strong project/program leadership experience, including managing teams on complex, multi-workstream engagements and ensuring scientific and editorial quality.

Excellent writing, editing, and executive communication skills; ability to craft clear narratives from technical analyses.

Strong analytical fluency and comfort engaging with complex datasets and statistical outputs (hands-on analytics not required but highly valued).

Client-service orientation, sound judgment, high attention to detail, and ability to operate effectively in a fast-paced environment.

Proficiency with Microsoft Office (PowerPoint, Excel, Word, Outlook).

Pay Range: $90,000-$110,000

This is the pay range the Company believes it will pay for this position at the time of this posting. Consistent with applicable law, compensation will be determined based on job-related, non-discriminatory factors including but not limited to work experience, skills, certifications, and geographical location. The Company reserves the right to modify this pay range at any time.

Real Chemistry is proud to be Great Place to Work® certified; check out what our people shared about our culture and workplace on our Great Places to Work Profile here.

We believe we can do our best when feeling our best, which is why we’ve put together a benefits program designed to give you the support you and your family need at every stage of life. Real Chemistry offers a comprehensive benefit program and perks, tailored to your region. Globally, this includes offices in our key markets with free snacks to keep you running all day long, generous holiday and paid time off, options for private medical, dental, and vison plans, and support in saving for the future.

Other perks include mental wellness coaching and support and access to more than 13,000 online classes with LinkedIn Learning. Learn more about our great benefits and perks and search specific offerings in your region at: www.realchemistrybenefits.com.

At Real Chemistry, we believe we're at our best when we're connected. Our Real Hybrid and Regional Teams (Real HART) approach is designed to foster collaboration, learning, innovation, and meaningful relationships while providing flexibility where appropriate. Because our workforce spans multiple countries, regions, and client needs, work arrangements may vary by role and location. Some positions offer hybrid or remote flexibility, while others require regular in-office presence.

For example, certain teams and regions, including some of our UK operations, have office-based requirements. Your recruiter will discuss the specific expectations for the role you're pursuing during the interview process and keep you informed throughout the hiring journey. For employees located within a one-hour commute of a Real Chemistry office, we require in-person attendance two days per week, either from a Real Chemistry office or when working onsite with clients.

Employees in regions without a nearby office may work remotely and come together throughout the year for collaboration, culture-building, learning, and team connection opportunities. While these guidelines reflect our current workplace model, we understand that everyone’s circumstances are unique. If you require additional flexibility, we welcome an open conversation with your recruiter and our HR team to discuss your needs and determine what may be possible.

Real Chemistry is an Equal Opportunity employer. We continually strive to build and sustain an inclusive and equitable work environment where our employees feel empowered to leverage all they bring from their personal lived experience and professional expertise, to make our team the best in the industry. We encourage motivated and qualified applicants to apply without regard to race, color, religion, sex (including pregnancy), sexual orientation, gender identity/expression, ethnic or national origin, age, physical or mental disability, genetic information, marital information, or any other characteristic protected by federal, state, or local employment discrimination laws where Real Chemistry operates.

Should you require accommodations throughout the interview process please let your recruiter know.

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